The transit through the Sound is one of this voyage’s highlights. Connecting the Labrador Sea with the Irminger Seat, Prince Christian Sound or “Prins Christian Sund” in Danish is named after Prince (later King) Christian VII (1749-1808). 100 km (60 miles ), long and at times just 500 m (1500 ft) wide, this majestic and spectacular fiord throws you back into a Viking era – flanked by soaring snow-topped mountains, rock-strewn cliffs and rolling hills, it is as if time has stood still and one easily forgets that this is the 21st century. As you marvel at the sheer size of the mountains that surround you, with the Arctic waters lapping deceptively at the hull, revel in the silence enveloping you. Icebergs float serenely by, carrying with them the ages of time. Be sure to wear warm clothing as this is one spectacle that you do not want to miss.

The largest town in southern Greenland, Qaqortoq has been inhabited since prehistoric times. Upon arrival in this charming southern Greenland enclave, it's easy to see why. Qaqortoq rises quite steeply over the fjord system around the city, offering breath-taking panoramic vistas of the surrounding mountains, deep, blue sea, Lake Tasersuag, icebergs in the bay, and pastoral backcountry. Although the earliest signs of ancient civilization in Qaqortoq date back 4,300 years, Qaqortoq is known to have been inhabited by Norse and Inuit settlers in the 10th and 12th centuries, and the present-day town was founded in 1774. In the years since, Qaqortoq has evolved into a seaport and trading hub for fish and shrimp processing, tanning, fur production, and ship maintenance and repair.

Northeast of Qaqortoq and at the end of a fjord, Hvalsey is one of the best examples of South Greenland’s many scattered ruins from the Norse period. Today the area is used for sheep-grazing, but until the 15th century the settlement at Hvalsey, and specifically Hvalsey’s church, played an important part. Christianity had spread its influence throughout Europe and eventually had reached remote Greenland, where it established itself in the country in 1000 AD. Hvalsey Church was built in the 14th century and is the best preserved of the churches in Greenland from that period. Apart from the church walls, historical ruins from the time of the Norse are just a few meters away.

Located just north of the Arctic Circle, Sisimiut is the northernmost town in Greenland where the port remains free of ice in the winter. Yet it is also the southernmost town where there is enough snow and ice to drive a dogsled in winter and spring. In Sisimiut, travelling by sled has been the primary means of winter transportation for centuries. In fact, the area has been inhabited for approximately 4,500 years. Modern Sisimiut is the largest business center in the north of Greenland, and is one of the fastest growing Greenlandic cities. Commercial fishing is the lead economy in the town‘s thriving industrial base.

Known as the birthplace of icebergs, the Ilulissat Icefjord produces nearly 20 million tons of ice each day. In fact, the word Ilulissat means “icebergs” in the Kalaallisut language. The town of Ilulissat is known for its long periods of calm and settled weather, but the climate tends to be cold due to its proximity to the fjord. Approximately 4,500 people live in Ilulissat, the third-largest town in Greenland after Nuuk and Sisimiut. Some people here estimate that there are nearly as many sled dogs as human beings living in the town that also boasts a local history museum located in the former home of Greenlandic folk hero and famed polar explorer Knud Rasmussen.

The name Kangerlussuaq means "Big Fjord" in the local Kalaallisut language. The settlement of about 500 people is located in western Greenland on flat land at the head of a fjord with the same name. Kangerlussuaq is the site of Greenland's largest commercial airport and most of the economy here is dependent on the air transportation hub and tourism. The rugged lands around the settlement support terrestrial Arctic fauna including muskoxen, caribou, and Gyrfalcons.

Nuuk, meaning “the cape”, was Greenland’s first town (1728). Started as a fort and later mission and trading post some 240 kilometers south of the Arctic Circle, it is the current capital. Almost 30% of Greenland’s population lives in the town. Not only does Nuuk have great natural beauty in its vicinity, but there are Inuit ruins, Hans Egede’s home, the parliament, and the Church of our Saviour as well. The Greenlandic National Museum has an outstanding collection of Greenlandic traditional dresses, as well as the famous Qilakitsoq mummies. The Katuaq Cultural Center’s building was inspired by the undulating Northern Lights and can house 10% of Nuuk’s inhabitants.